标签：#biot

Gidi Littwin's new AI startup, Hemispheric, makes diagnostic brain scans for conditions like depression, PTSD, and Parkinson’s. He wants the technology to be as cheap and easy as a blood test.

The funding discussions point to investor interest in applying AI to make breakthroughs in life sciences.

Researchers cobbled together funding and time to show how quantum computing could aid in the development of drugs to help underserved populations and combat rare diseases.

When we last sat down with Jobs at TechCrunch Disrupt nearly three years ago, his firm Yosemite was brand new and biotech was still reeling from its post-pandemic crash. Now, the venture outfit has a team of 17; a cluster of blockbuster drugs are all losing patent protection in roughly the same window, creating all kinds of new opportunities; and AI has gone from a curiosity to, in Jobs's words, a huge part of what Yosemite does. "I didn't expect Yosemite to be moving this fast," he said.

Pull a hot steel bolt out of a furnace and quench it in oil, and a fair question is: does the bolt cool from the outside in, with a sharp temperature difference between its skin and its core, or does the whole thing drop in temperature more or less together? The answer is not obvious from the part itself. A thin copper washer and a thick ceramic block behave very differently in the same bath, even at the same starting temperature. The Biot number is the small calculation that settles this question before you commit to any heavy analysis. It tells you, in a single dimensionless figure, whether an object can be treated as having one uniform temperature or whether you must resolve a temperature gradient inside it. That distinction changes the math from a one-line exponential decay to a partial differential equation. Why this calculation matters Transient heating and cooling problems show up everywhere: heat-treating metal parts, quenching forgings, cooling electronics, baking or chilling food, warming up an engine block. In every one of these, the engineer wants to know how the temperature changes over time. The hard version of that question requires solving the heat conduction equation across the body, with position and time as variables. The easy version is the lumped-capacitance model, which treats the whole object as a single point at one temperature. It reduces the problem to a simple first-order exponential. The catch is that the lumped model is only valid when internal conduction is fast compared with surface convection. The Biot number is exactly the check that tells you whether that condition holds. Skip the check and apply the lumped model where it does not belong, and you can badly mispredict cooling times, residual stresses, and the risk of cracking from thermal gradients. The core formula The Biot number compares two thermal resistances. One is the resistance to conducting heat through the inside of the solid. The other is the resistance to carrying heat a

Ties van der Meer doesn’t know how many siblings he has. The 47-year-old was conceived at a private fertility clinic in the Netherlands using sperm provided by an anonymous donor. After the Netherlands banned anonymous donation in 2004, the doctor who ran the clinic destroyed records that might have identified those donors, he says. He…

It’s not easy to transplant a whole human eye. The surgery is difficult. And the eyes themselves start to degenerate as soon as they’ve left the body. When surgeons attempted it a few years ago, the newly-transplanted eye wasn’t able to see. But researchers believe they might have a solution: a device that maintains and…

As the parent of two little girls, I often think about how their childhood is different from mine. The seven-year-old is learning about AI at school. The five-year-old is given internet-based homework every week. And they are both absolutely repulsed by the idea of smoking. That was not the prevailing sentiment when I was young.…

Listen to the session or watch below Billions of dollars are flooding into efforts to reverse aging as scientists explore ways to return cells to a younger state. But how far off are these experimental treatments? Will they really work? Watch a conversation exploring longevity’s new focus. Speakers: Mary Beth Griggs, science editor and Jessica…

Anthropic's Claude Science is a workbench that gives scientists one environment to do computational research, saving them from the need to bounce between databases, pipelines, and tools.

It's "an exciting advance in efforts to restock the antibiotic arsenal."

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It’s been hot in London this week. Really hot. A dangerous heat wave has hit Western Europe. Yesterday, the UK recorded its highest ever June temperature at 36.1 °C (about 97 °F). But as the weather app on my phone confirmed, it felt like 39 °C. It’s frightening that we are seeing such temperatures in…

The common cold comes for us all—often more than once a year. And there is no way to prevent it. The best you can do is take vitamin C and stay away from people with the sniffles. Now, the payment company Stripe, founded by brothers Patrick and John Collison, says it will fund a new…

The biodegradable material can help improve healing after surgery—or an avocado-related accident.

Coherence Neuro has started testing a brain-computer interface that could one day use electrical stimulation to prevent tumors from growing.

This week, I covered the story of Casey Harrell—a man with ALS who is “the first power user” of a brain implant, according to the researchers who worked with him. Harrell is paralyzed and unable to speak coherently without the device. He has now spent almost three years using a brain-computer interface (BCI) that enables…

Casey Harrell has had a set of electrodes embedded in his brain for almost three years. Harrell, who has amyotrophic lateral sclerosis (ALS) and is paralyzed, first used his brain-computer interface (BCI) to “speak” sentences with the help of a research team in 2023. Since then, Harrell has clocked thousands of hours of use. He…

MIT Technology Review Explains: Let our writers untangle the complex, messy world of science and technology to help you understand what’s coming next. You can read more from the series here. Your brain lives in the dark space of your skull. Yet it knows when the wind lifts the hairs on your skin, when your heart is…

Earlier this week, Life Biosciences, a biotech company focused on reversing age-related diseases, announced that it had dosed its first volunteer. A person with glaucoma has had an experimental treatment injected straight into their eyeball. The idea is to try to treat the disease—which can cause vision loss—by regenerating healthy nerves in the eye. But…